Endocrine Abstracts

Background: Adrenal venous sampling (AVS) is considered the gold standard for differentiating an aldosterone- producing adenoma (aPA) from bilateral adrenal hyperplasia (BAH)Objective: The aim of this study is to present our experience with this method in our hospital.Methods: We performed a retrospective analysis of 105 patients who underwent the AVS protocol at our centre between 2015 and 2022 for PA.Result...

Background: Adrenal venous sampling (AVS) is the gold standard to differentiate patients with unilateral primary aldosteronism (UPA) from those with bilateral disease (BPA). As this is an invasive method, there are a lot of different scoring systems developed for primary aldosteronism (PA) subtyping. Integer scoring system is one of those established for BPA subtyping.Objective: The aim of this study was to evaluate the efficiency of using the online Int...

Purpose: Adrenal vein sampling (AVS) is the gold standard method for subtyping primary aldosteronism (PA). A certain number of PA patients had unilateral successful AVS, concomitant autonomous cortisol secretion or indeterminate lateralization index (LI 2.5–4), which made correct interpretation of AVS data impossible. The aim of our study was to determine whether absolute aldosterone concentration can predict the subtype of PA in patients with inconclusive AVS data.<p...

Background: Learning through various online platforms is very common nowadays and its popularity has increased especially during the pandemic period. Nowadays, medical professionals are turning more than ever to online education through available online books, websites, and various online platforms. The aim of this study was to show that virtual training can improve the knowledge and confidence of young endocrinologists.Methods: The Croatian Section for ...

Introduction: Mitotane is widely used to treat adrenocortical carcinoma (ACC) and remains the mainstay of treatment along with surgery. The aim of this study is to evaluate the adverse side effects of mitotane treatment.Materials and Methods: This retrospective study included 36 patients with ACC, ENSAT stage I- IV, who were treated with mitotane in an adjuvant or palliative setting. Patients with ENSAT stage IV who died within 6 months after surgery wer...

Background: The aim of this study was to evaluate the outcomes of medical treatment in patients with active acromegaly.Material and Methods: We performed a retrospective analysis of 163 patients (101 female, age at diagnosis 47.2&pm;13.4 years) treated between 1990 and 2020., of which 53 were on medical treatment (32.5%). Remission rate after pituitary surgery was 66.5% (n=105/158; 5 patients refused surgery). Patients who did not achieve remiss...

Background: Steroid synthesis inhibitors, like metyrapone, osilodrostat, and ketoconazole are used as second-line treatment in all types of endogenous Cushing’s syndrome (CS). However, a direct comparison of these three drugs is missing. This study aimed to compare these drugs in the short-term therapy of CS.Design: Retrospective multicenter study involving 16 centers worldwide.Methods: Patients with CS treated with metyrapone...